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Cannabidiol, better known as CBD, is one of over a 100 different types of cannabinoids discovered to date. CBD oil is typically registered and marketed as a nutritional and/or health supplement and is showing up in everything form of CBD products from cookies and chocolates, to smoothies and designer waters. The Food and Drug Administration in the US has also approved the first CBD drug to treat rare forms of epilepsy in children after successful clinical trials. 

And unlike its psychedelic cousin from the cannabis plant tetrahydrocannabinol (THC), CBD has basically no recreational properties but is often touted as a type of wonder drug that helps a myriad of ailments and conditions (amongst others, chronic pain, multiple sclerosis, etc.) through its interaction with the endocannabinoid system. Not only that, but research is showing that controlled CBD administration is both effective and safe. And with the reported side effects of CBD oil being almost non-existent when compared to many pharmaceutical treatments, many people are turning to CBD oil for symptom relief. 

But is this really the case? Are there really no side effects of CBD oil? And if there are CBD side effects, what are they? Does CBD work differently or are high levels of CBD content more dangerous? Below, uWeed explains you how safe CBD really is and what potential side effects there might be.

IS CBD REALLY SAFE? Side-effects studied by who

The World Health Organization (WHO) recently released a report stating that: "To date, there is no evidence of public health related problems associated with the use of pure CBD.” The same report also stated that there is no evidence currently available showing that cannabis oil is either physically or psychologically addictive, making it an excellent long-term treatment option for many people. 

This report is largely based on emerging evidence from several studies showing that CBD is non-toxic (non-psychoactive), and well tolerated by most patients even with chronic use at high dosages of up to 1,500 mg/day. In addition, they also found that there is no evidence showing that CBD has any effect on psychomotor or psychological function, nor does it cause changes in, or affect any other physiological parameters such as heart rate, blood pressure or body temperature at controlled dosages. 

And in comparison with other drugs often used for the treatment of many serious medical conditions, including medical marijuana, the profile of CBD side effects is much better, helping to improve patients' compliance and adherence to treatment. 

However, some reports also mention certain contraindications and side effects of CBD oil usage for some and everyone should seek medical advice before starting a regular intake of CBD to avoid or limit potential side effects.




Hemp oil can act as a blood thinner by raising the blood thinning compound called coumadin in the body. This means that for people who are already suffering from low blood pressure, certain blood diseases or bleeding disorders such as haemophilia or von Willebrand disease, CBD can be risky.



CBD can also interact with certain medications by inhibiting drug metabolism in the liver in a similar way in which grapefruit juice does. A good rule of thumb is to always consult your doctor before using CBD with other medications, especially if your pharmacist contraindicated the ingestion of fruit juice, citrus or fermented products.



Emerging research into CBD for movement disorders such as Parkinson’s disease is showing promise as potentially treating and/or preventing the debilitating symptoms linked to oxidative stress and neurodegeneration associated with these conditions. However, some early research suggests that taking high doses of cannabidiol might make muscle movement and tremors worse for some patients.



CBD side effects for some people can include gastrointestinal issues. This can sometimes lead to a nausea and a loss of appetite that some people find unpleasant. In some individuals this is purely due to CBD not being tolerated well. For others, it might indicate that there is another ingredient in their CBD oil that they are sensitive to. Try to either reduce the CBD dosage or purchase a purer product with fewer ingredients.


Cannabinoid receptors are spread throughout the body, including the mouth and salivary glands. CBD interacts with these receptors, sometimes causing a dry mouth feel by inhibiting the secretion of saliva. Although this can be unpleasant, this CBD side effect is easily rectified by drinking a glass of juice or water.


Because everyone is unique, with each of us having different needs, body compositions, health profiles and physical conditioning, everyone also metabolises CBD differently. This means that some people can experience certain side effects of CBD drops while for yet some others, using CBD may be completely contraindicated. Always speak to your doctor before starting any type of treatment, even natural options such as CBD oil.

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